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7-OXO (7-KETO DHEA)

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7-OXO by Brawn Nutrition is a food supplement whose active ingredient improves fat burning during a long-term weight loss diet. It produces numerous effects that reduce a negative impact of calorie restriction on the metabolic rate.
7-OXO, otherwise known as 7-oxo-dehydroepiandrosterone is a metabolite of the steroid hormone dehydroepiandrosterone (DHEA) which improves the fat burning process. This active ingredient is found naturally in the body and inhibits the processes responsible for slowing down the metabolism. Despite being derived from a steroid compound, 7-OXO does not show this effect.

Impact of the active substance on cortisol
Cortisol is a hormone from a glucocorticoid group secreted in the adrenal cortex during stressful situations. It induces catabolic processes that can help the body fight stress. One of them is a strict weight loss diet. A too low intake of calories in the diet or a long calorie restriction are stressors for the body and consequently the secretion of this hormone from the adrenal glands increases. This lowers the metabolic rate and can even promote the accumulation of body fat.
7-OXO is converted in the body into two other metabolites of DHEA: 7α-hydroxy-DHEA and 7β-hydroxy-DHEA. This process takes place in the presence of the enzyme 11β-hydroxysteroid dehydrogenase type 1. The main function of this compound is the conversion of inactive cortisone and corticosterone into cortisol. As the 7-OXO pool has increased, the impact of this enzyme on stress hormone production is reduced. This involves inhibiting its activity which promotes the accumulation of body fat during a rigid diet.

7-OXO and mitochondria
The active substance stimulates the activity of the enzymes responsible for regulating the permeability of the mitochondrial membrane. Mitochondria are cellular organelles that function as a furnace that causes the conversion of energy substrates to ATP. An increase in the permeability of the mitochondrial membrane allows glucose and fat molecules to penetrate inside them. This ensures effective fat burning and high energy levels, particularly desired during a period of body fat reduction.
Brawn Nutrition 7-OXO is a food supplement that provides effective fat burning in the last phase of a long-term fat reduction diet. The active substance in this formula inhibits the negative adaptation of the body during this period, associated with a lower metabolic rate. Because of this, the supplement is recommended for people who want to stay as thin as possible and maintain high energy levels and low stress.


Dosage
From 1 to maximum 4cps per day, divided. Do not exceed 6 weeks.


Specific References

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