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S4 MAX is the brand new product previewed exclusively on SuppsIT from the exceptional Core Labs brand.
A product based on S-3- (4-acetylamino-phenoxy) -2-hydroxy-2-methyl-N- (4-nitro-3-trifluoromethyl-phenyl) -propionamide), a compound also known as Acetamidoxolutamide or Andarin for short S4 or GTX 007, with the ability to modulate androgen receptors, used in particular as a means to markedly support body recomposition, promoting muscle growth and fat loss without minimal side effects.
Androgen (AR) receptors are a group of receptors sensitive to the effects of androgens and other steroid compounds, allowing the expression of corresponding genes to be regulated. They allow the growth of healthy muscle and bone tissue, without causing adverse effects attributable to excessive testosterone activity. Since the compounds are generally not subject to catalyzed changes in aromatase, they provide a good alternative to the adoption of dangerous and banned androgenic anabolics and their derivatives. Andarine is not the strongest of the SARMs, but its selective action of specific androgen receptors gives great opportunities to develop the desired structures. S4 has high localized affinity in muscle and bone tissues. The complete activation by means of which accelerates the development of skeletal muscle and the mineralization of the bone are confirmed by the more effective synthesis of osteoblasts. GTX 007 stimulates the adrogen receptors of fat deposits by reducing the lipoprotein lipase within them and leading to a reduction in stored fat. It is not subject to aromatase catalyzed reactions, becoming essentially side-effect free from excessive estrogen activity GTX 007, being unmethylated, has a high level of safety for the liver. It does not cause an increase in blood pressure or lead to negative changes in the lipid profile. S4 selectively acts as an anabolic agent, supporting muscle tissue growth and bone mineralization, with concomitant fat loss. The product allows an increase in resistance, muscle density and hardness, and a decrease in fat, increasing vascularization, constituting an indispensable support for the entire muscle growth. S4 belongs to a class of substances known as SARMs or selective androgen receptor modulators. They bind to the androgen receptor but selectively by creating receptor binding activity with specific androgen receptors (musculoskeletal tissue) and not with others (prostate, hair follicles, etc.), hence their name. The advantage of SARMs such as S4 is that they have no androgenic activity in non-musculoskeletal tissues. S4 was designed for the treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as the lead compound. S4 is effective, not only for maintaining lean body mass (LBM) but also for increasing muscle tissue.
Due to its androgenic activity in muscle tissue, S4 is a good agent for strength gains without creating large weight gains. Dosages above 50mg are the sweet spot if pursuing such gains. Also due to its anabolic nature, these strength gains will come with associated gains in lean mass, albeit to a lesser extent than other more anabolic SARMs such as Ostarine. Weight gain with S4 intake can only be of excellent quality, and the lean mass and strength gained during the cycle (for the most part) is not lost after the cycle. The half-life of S4 is approximately four hours, which means that the daily dose must be divided into several administrations throughout the day. Also due to this short half-life, users have found that taking one of these "pre-workout" doses offers greater performance in the gym.

How does it work?
The molecule by binding to the target androgen receptor activates it by altering the expression of genes and increasing protein synthesis, thus building new muscle. Hence, they essentially cause muscle growth in the same way that steroids do, but unlike testosterone and other banned and harmful anabolic steroids and prohormones, SARMs do not produce harmful effects on prostate and other organ growth. secondary sexual. SARMs thus represent immense muscle building potential for bodybuilders, fitness and athletes.

Obvious capabilities:
S4 (3mg / kg / day) was able to restore skeletal muscle (ie, soleus) and strength in castrated rats; important and applicable result for the treatment of muscle atrophy in males. A 120-day study compared S4 and dihydrotestosterone (DHT) in the treatment of ovariectomized rats demonstrating that S4 was able to maintain bone mass and strength at normal control levels demonstrating greater efficacy than DHT. S4 has also shown the ability to improve skeletal tissue, muscle strength, increase lean body mass (LBM), reduce body fat, and prevent bone loss.

Dosages for Cutting
A protocol of 50 mg / day for 4-8 weeks is ideal for cutting purposes for the majority of users. However some follow a 5 day On and 2 off protocol where S4 is used for 5 days followed by a two day break (after which the cycle repeats). The recomping effect of fat loss and increased muscle mass at the same time is what most users are looking for. One of the most important factors in a recomping is time. Since you are trying to achieve multiple goals, this takes a longer period of time for you to notice good effects of "Recomp". S4 is taken orally, as it is not methylated, it is not toxic to the liver like other AAS / PH / DS. This prevents many side effects, making it possible to cycle longer than 6 weeks, enough time to get a good physical "Recomp".

Dosage for the Recomp
A protocol with a dosage of 70mg / day for 4-8 weeks will give good "Recomp" effects. The diet must be optimized so calories must be kept just above the maintenance level with at least 30% coming from lean protein sources for the best "Recomp" effect. Of course, the "Recomp" and "Bulking" effects can be greater if S4 is used in conjunction with a more anabolic SARM such as Ostarine or LGD.

However, due to some possible individual side effects to the eye, it is recommended to follow a "5 days on, 2 days off" cycle, where Andarine is taken for 5 days, followed by a 2 day break (weekend).
At the end of the cycle, PCT with the appropriate products is recommended.
Also useful products such as LiveR, LiveR PRO or Liv.52, Liv52DS, as well as Arjuna or Abana, Karela, Coletix.

Specific References

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